Expresión de búsqueda: CRK-ASSOCIATED SUBSTRATE PROTEIN 
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Descriptor Inglés:   Crk-Associated Substrate Protein 
Descriptor Español:   Proteína Sustrato Asociada a CrK 
Descriptor Portugués:   Proteína Substrato Associada a Crk 
Categoría:   D12.644.360.024.295
D12.776.157.057.022
D12.776.476.024.374
D12.776.744.425
Definición Inglés:   Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION. 
Nota Histórica Inglés:   2006(2004) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   50765 
Identificador Único:   D050719 

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